The Effect of Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine or Bupivacaine

Stopped early · Not applicable · Has a placebo group

Conditions studied: Anesthesia, Local, Shoulder Surgery

In brief

This study will test the hypothesis that adding dexamethasone significantly prolongs the duration of ropivacaine and bupivacaine analgesia, and that the magnitude of the effect differs among the two local anaesthetics.. Participants will be patients undergoing shoulder surgery with an interscalene nerve block.

Key facts

Study ID

NCT00801138

Run by

The Cleveland Clinic

People needed

218

Starts

2008-11-01

Expected to finish

2010-11-01

Last updated by the study team

2017-05-01

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age between 18 and 75 years
• Patients undergoing shoulder procedures, such as rotator cuff repair, capsular shift, shoulder arthroplasty, subacromial decompression

You may not qualify if…

• Contraindications to interscalene block (Coagulopathy, infection at the needle insertion site, moderate to severe chronic obstructive pulmonary disease, contralateral pneumothorax or diaphragmatic paralysis)
• Pregnancy
• Pre-existing neuropathy involving the surgical limb
• Systemic glucocorticoid treatment (for 2 weeks or more) within six months of surgery
• Chronic opioid use (greater than 30 mg oral oxycodone equivalent per day)

Where it is running

• Cleveland Clinic — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.