Pelvic Fractures and Radiation Therapy for Cervical Cancer

Status unconfirmed

Conditions studied: Cervical Cancer, Endometrial Cancer, Vaginal Cancer

In brief

The goal of this study is to estimate how often pelvic fractures occur in women treated with radiation therapy for either newly diagnosed or recurrent cervical, endometrial, or vaginal cancer. The study will also estimate the changes in bone mineral density and the changes in the blood that relate to "bone turnover". High bone turnover can weaken bones and make you more likely to break a bone.

Key facts

Study ID

NCT00800644

Run by

M.D. Anderson Cancer Center

People needed

239

Starts

2008-11-05

Expected to finish

2020-11-30

Last updated by the study team

2020-01-13

Who can join

Age: any. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Patients with histologically confirmed primary or recurrent cervical , endometrial or vaginal cancer. All stages, grades and histologic subtypes will be eligible except neuroendocrine.
• Patients treated with definitive radiation therapy. Patients receiving extended field radiation or brachytherapy in addition to pelvic radiation are eligible. Patients treated with surgery, chemotherapy and/or hormonal therapy in addition to radiation therapy are also eligible.
• Patients must sign an approved informed consent document.

You may not qualify if…

• Patients undergoing palliative intent radiation therapy for advanced disease.
• Patients who received prior radiation to the pelvis.
• Patients with an existing pelvic fracture within the proposed radiation field.
• Patients unwilling or unable to provide informed consent for the study.
• Patients with bone metastases.
• Neuroendocrine features present.
• Patients weighing more than 300 lbs are excluded as they cannot be adequately studied in axial skeleton with current bone mineral density software.

Where it is running

• University of Texas MD Anderson Cancer Center — Houston, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.