The Body's Response to Food Intake in Older Adults

Completed · Not applicable

Conditions studied: Elderly

In brief

We propose to critically evaluate the effects of energy-yielding fluids and solids on acute appetite variables, daily food intake, and specific endocrine and metabolic response to food in the elderly. The results of these studies will provide further evidence to support that nutrition may provide safe and effective non-pharmacological therapies to counter the compromised regulation of energy balance experienced by many elderly people.

Key facts

Study ID

NCT00798408

Run by

Purdue University

People needed

35

Starts

2006-02-01

Expected to finish

2008-01-01

Last updated by the study team

2013-09-24

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age range: 60 years and older
• Body mass index between 20-29 kg/m2
• Weight stable (< 2 kg weight change within last 6 months)
• Non-smoking
• Constant habitual activity patterns within last 3 months
• Clinically normal blood profiles (specifically, normal liver and kidney function; normal complete blood count (non-anemic); fasting blood glucose <110 mg/dl)
• Not taking medications known to influence appetite or metabolism
• Non-diabetic
• Resistive exercise training (≤2 times a week) based on reported physical activity levels (questionnaire)
• Active fitness level (≤3, 30-minute aerobic exercise sessions/week)
• Confirmation of acceptability of eating the study test foods (solids and fluids)

You may not qualify if…

• Age: <60 years
• Body mass index: outside of the 20-29 kg/m2 range
• Gained or lost > 4.5 kg within the last 6 months
• Smoker (currently or within the last year)
• Intermittently been involved in a diet and/or exercise program within the last 3 months
• Clinically abnormal blood profiles as identified by our study physician, Arthur Rosen, MD
• Taking medications (currently or within the last 3 months) known to influence appetite or metabolism
• Abnormal heart function (interpreted by a cardiologist) and assessed (for study exclusion) by our study physician, Arthur Rosen, MD
• Clinically diagnosed as diabetic
• Did not perform resistive exercise training (currently or within the last 3 months) based on reported physical activity levels (questionnaire)
• Perform ≥ 2, 30-minute aerobic exercise sessions/week (currently or within the last 3 months) based on physical activity levels (questionnaire)
• Study foods are found to be unacceptable for consumption by the subject

Where it is running

• Purdue University — West Lafayette, Indiana, United States

Full record on ClinicalTrials.gov

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