Using Functional MRI to Evaluate Cognitive Behavioral Therapy Treatment Response in Adults With Chronic Pain

Completed · Phase 1/Phase 2

Conditions studied: Chronic Pain

In brief

Chronic pain is a condition in which pain continues for 1 month or more beyond the usual recovery period for an injury or illness or persists for months or years due to a chronic condition. A commonly used type of psychotherapy called cognitive behavioral therapy (CBT) has been found to be effective in treating people with chronic pain. The purpose of this study is to determine whether and how CBT geared specifically for treating chronic pain can change the way the brain responds to painful emotional and physical stimuli.

Key facts

Study ID

NCT00796536

Run by

University of Vermont

People needed

40

Starts

2009-06-01

Expected to finish

2011-07-01

Last updated by the study team

2013-02-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• At least 6 months of musculoskeletal non-neuropathic pain confined to lumbar or thoracic back
• Meets study threshold for severity of typical pain of 4 or more on a 10-point scale adapted from the McGill Pain Questionnaire
• Has ongoing standard pain management from a physician
• Agrees to participate in this research study

You may not qualify if…

• Malignancy
• Reflex sympathetic dystrophy and/or naturopathic pain
• Opioid medication use
• Substance use disorder
• Neurological disorder, such as epilepsy, stroke, or other medical condition that could confound or interfere with the current study
• Major depression or/and dysthymia
• Post traumatic stress disorder or panic disorder
• Left-handedness
• Pregnancy
• History of illicit drug use (cocaine, cannabis, heroin) that can result in altered cognition
• Exceeding the weight limit on the MRI scanner
• Suffering from claustrophobia
• Any of the following: cardiac pacemakers, auto defibrillators, neural stimulators, aneurysm clips, metallic prostheses, cochlear implants, any implanted devices (pumps, infusion devices, stents), permanent eye make-up, intrauterine devices, shrapnel injuries

Where it is running

• MindBody Medicine Clinic — Burlington, Vermont, United States

Full record on ClinicalTrials.gov

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