Effect of Milnacipran on Pain Processing and Functional Magnetic Resonance Imaging (fMRI) Activation Patterns in Patients With Fibromyalgia

Stopped early · Phase 3 · Has a placebo group

Conditions studied: Fibromyalgia

In brief

The purpose of this study is to evaluate the effect of milnacipran on how the brain processes pain in patients with fibromyalgia and to assess the relationship between this effect and brain activation patterns during functional magnetic resonance imaging.

Key facts

Study ID

NCT00793520

Run by

Forest Laboratories

People needed

2

Starts

2008-11-01

Last updated by the study team

2010-07-01

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of fibromyalgia defined by 1990 American College of Rheumatology (ACR) criteria
• Visual analog pain score between 40 and 90 mm
• Right-hand dominance

You may not qualify if…

• Suicidal risk
• Substance Abuse
• Pulmonary dysfunction
• Renal impairment
• Active cardiac disease
• Autoimmune disease
• Uncontrolled narrow-angle glaucoma
• Active liver disease
• Cancer
• Active peptic ulcer disease or a history of inflammatory bowel disease or celiac sprue
• Unstable endocrine disease
• Prostatic enlargement

Where it is running

• Forest Investigative Site — Ann Arbor, Michigan, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.