Recovery From Psychosis in Schizophrenia - The Impact of Cognitive-Behavioral Therapy

Completed · Not applicable

Conditions studied: Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder

In brief

This study examines the impact of Cognitive-Behavior Therapy (CBT) on symptoms, physiological arousal, stressors, and the ways to deal with them in individuals with schizophrenia and related disorders. The primary aim of this study is to investigate the role cognitive coping strategies play in mediating the link between stress, physiological arousal, and psychotic symptoms in individuals with schizophrenia during recovery from psychosis.

Key facts

Study ID: NCT00791440
Run by: New York State Psychiatric Institute
People needed: 34
Starts: 2008-11-01
Expected to finish: 2012-06-01
Last updated by the study team: 2012-12-13

Who can join

Age: 18 and older, up to 50. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Males and females between ages 18-50.
Have capacity to give informed consent.
English speaking.
Have a DSM-IV diagnosis of schizophrenia, or schizoaffective disorder, or schizophreniform disorder.
Presence of active psychosis as indexed by ratings ≥3 on any hallucinations and delusions items of the Scale for Assessment of Positive Symptoms (SAPS).

You may not qualify if…

Lacks capacity to give informed consent.
Diagnosis of mental retardation (IQ < 80).
Have history of neurological disorders or medical conditions known to seriously affect the brain.
Have history of cardiac conditions or hypertension; current use of anti-cholinergic, beta-blockers, anti-histamine, or anti-hypertensive medication; abnormalities on ECG.
Have used street drugs within the past 4 weeks.

Where it is running

Columbia University & New York State Psyciatric Institute — New York, New York, United States

Full record on ClinicalTrials.gov

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