ERG/EOG Study in AMD Patients Treated With Ranibizumab
Completed
Conditions studied: Age-Related Macular Degeneration
In brief
This is an open-label study assessing electrophysiologic testing of the retina with Electoretinogram (ERG) /Electrooculogram (EOG) tests in patients with exudative age-related macular degeneration (AMD). The standard FDA-approved treatment for wet AMD is ranibizumab (Lucentis). This study focuses on the ERG and EOG tests to evaluate retinal responses to ranibizumab treatment in AMD.
Key facts
- Study ID
- NCT00791427
- Run by
- Retina Center, Minnesota
- People needed
- 10
- Starts
- 2008-11-01
- Expected to finish
- 2011-09-01
- Last updated by the study team
- 2015-05-08
Who can join
Age: 55 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Ability to provide written informed consent and comply with study assessments for the full duration of the study
- Age >55 years
- Patients to be included in the study must have AMD with choroidal neovascularization
- BCVA between 20/20 - 20/400
- Lesion size less than or equal to 12 MPS disc areas
You may not qualify if…
- Prior treatment with an anti-VEGF agent within 6 months of enrollment in this study
- Pregnancy (positive pregnancy test)
- Premenopausal women not using adequate contraception. The following are considered effective means of contraception: surgical sterilization or use of oral contraceptives, barrier contraception with either a condom or diaphragm in conjunction with spermicidal gel, an IUD, or contraceptive hormone implant or patch
- Prior enrollment in the study
- Any other condition that the investigator believes would pose a significant hazard to the subject if the investigational therapy were initiated
- Participation in another simultaneous medical investigation or trial
- Media insufficient to obtain a view
- Other causes of CNV not related to AMD
- Active ocular or peri-ocular infection
- Ocular surgery within 1 month prior to the study
Where it is running
- The Retina Center — Minneapolis, Minnesota, United States
Full record on ClinicalTrials.gov
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