Directly Observed Therapy for Community-Released HIV+ Prisoners
Completed · Not applicable
Conditions studied: HIV/AIDS, Substance Abuse
In brief
The aim of this study is to develop effective interventions for HIV-infected prisoners who are released to the community. The intervention that we will study will be directly observed therapy (DAART/DOT) and we will compare this to the current standard of care that involves self-administered therapy (SAT). All subjects will get transitional case management and all subjects with a prior history of opiate dependence will be offered opiate substitution therapy (buprenorphine or methadone). Hypotheses: * At the end of six months those receiving DAART will have a higher level of adherence to HAART as compared to the SAT group. * The DAART Intervention will result in subjects having lower viral loads and higher CD4 counts as compared to the SAT group. * At the end of six months, the DAART group will have a lower rate of recidivism to jail/prison as compared to the SAT group. * Over the year, the DAART group will be more likely to make repeated primary HIV care visits than the SAT group.
Key facts
- Study ID
- NCT00786396
- Run by
- Yale University
- People needed
- 151
- Starts
- 2004-07-01
- Expected to finish
- 2010-12-01
- Last updated by the study team
- 2014-08-20
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- HIV seropositive
- 18 years of age or older
- incarcerated for a minimum of 90days
- living in New Haven or Hartford
- currently on HAART or willing to begin HAART medications
You may not qualify if…
- Not meeting inclusion criteria
Where it is running
- Yale University-Yale Clinical Research — Hartford, Connecticut, United States
- Yale University School of Medicine — New Haven, Connecticut, United States
Full record on ClinicalTrials.gov
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