Evaluating the Effectiveness of a Community Exercise Program to Reduce the Risk of Metabolic Syndrome Among Black Americans
Completed · Phase 3
Conditions studied: Metabolic Syndrome
In brief
Black Americans with a family history of early heart disease tend to have a group of risk factors that can contribute to heart disease. These risk factors, which include excess body weight, high blood pressure, and high cholesterol, are known collectively as metabolic syndrome. This study will compare a community-based, coach-led exercise program to an individual, self-led home-based exercise program to determine which program is more effective at reducing the metabolic syndrome risk factors that can lead to heart disease.
Key facts
- Study ID
- NCT00783445
- Run by
- Johns Hopkins University
- People needed
- 204
- Starts
- 2008-12-01
- Expected to finish
- 2013-04-01
- Last updated by the study team
- 2014-03-11
Who can join
Age: 21 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Participating in the Johns Hopkins Sibling and Family Heart Studies
- Has metabolic syndrome components
- Self-identifies as Black American
You may not qualify if…
- Any clinical CAD
- Diabetes
- Major co-morbidity that precludes exercise (e.g., stroke, AIDS, cancer, neurological disorder, serious emphysema or exercise asthma, disabling arthritis)
- Resting systolic blood pressure greater than or equal to 160 mm Hg, resting diastolic blood pressure greater than or equal to 100 mm Hg, or exercise peak blood pressure greater than or equal to 250/115 mm Hg
- Known ejection fraction less than 40%
- Already participating in regular exercise, defined as 90 minutes per week of activities of greater than 5 metabolic equivalents (METS)
- Cardiac arrhythmias, including supraventricular tachycardia in the 5 years before study entry, any ventricular tachycardia, or greater than 4-beat runs of nonsustained premature ventricular contractions on baseline screening exercise testing
- Body mass index (BMI) greater than 45 kg/m2
- Alcohol or substance abuse in the 12 months before study entry
- A known abnormal exercise electrocardiogram and an abnormal thallium scan (double abnormal), a moderate to severe defect on thallium scan, or a coronary calcium score greater than 500 on a prior screening
- An abnormal exercise screening test supervised by a physician as part of this study
- Pregnant
- Current smokers if they have stated evidence of shortness of breath with normal exercises or a diagnosis of chronic obstructive pulmonary disease by their physician, as verified by medical records
Where it is running
- Johns Hopkins Bayview Institute for Clinical Translational Research — Baltimore, Maryland, United States
Full record on ClinicalTrials.gov
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