Autonomic Dysfunction and Spinal Cord Stimulation in Complex Regional Pain Syndrome

Stopped early · Not applicable

Conditions studied: Complex Regional Pain Syndrome

In brief

To demonstrate that spinal cord stimulator has an effect on sympathetic function (the one that give us the fight and flight response). Therefore, if the spinal cord stimulator has an effect on sympathetic function, the responses from CRPS patients to different stimuli will differ significantly pre and post SCS implant. If CRPS patients exhibit autonomic, CRPS patients could be stratified according to their sympathetic function pre-implant. It is expected that patients with a moderate/mild form of autonomic dysfunction will have better outcomes with the SCS.

Key facts

Study ID

NCT00780390

Run by

Vanderbilt University Medical Center

People needed

10

Starts

2008-01-01

Expected to finish

2010-01-01

Last updated by the study team

2026-07-27

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• CRPS patients meeting the inclusion criteria according to the International Association for the Study of pain task Force will be included in the study.
• Age: 18 to 65.
• Disease duration of at least 6 months.
• History of unsuccessful long lasting therapies: physical therapy, transcutaneous electrical stimulation and medication.

You may not qualify if…

• Presence of current or past pulmonary, hepatic, renal disease, arthritis, hematopoietic, and neurological diseases not related to CRPS.
• Anticoagulant therapy, cardiac pacemaker used.
• Pregnancy test for females is positive.

Where it is running

• Vanderbilt University — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

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