Curcumin (Tumeric) in the Treatment of Irritable Bowel Syndrome: A Randomized-Controlled Trial
Completed · Phase 4 · Has a placebo group
Conditions studied: Irritable Bowel Syndrome
In brief
Evidence exists to support low-grade inflammation as the inciting factor leading to visceral hypersensitivity and alteration in motility in irritable bowel syndrome.In the medical literature,there is ample in vitro and in vivo evidence supporting turmeric and its derivative curcumin as an antitumor, anti-inflammatory and antioxidant agent. We propose a randomized, placebo-controlled, double blinded, parallel treatment study evaluating the effects of turmeric on the symptoms of irritable bowel syndrome.
Key facts
- Study ID
- NCT00779493
- Run by
- Kaiser Permanente
- People needed
- 17
- Starts
- 2008-11-01
- Expected to finish
- 2009-06-01
- Last updated by the study team
- 2015-03-11
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Patients from the hospitals and clinics of the Southern California Permanente Medical Group who conform to the Rome III criteria and
- Age 18 years and above,
- Male or female,
- Able to give consent and follow the treatment plan and be able to answer surveys.
- Negative serum pregnancy test (females of childbearing potential only) and are willing to use an adequate method of contraception throughout the duration of the study.
You may not qualify if…
- Any of the following: diabetes, HIV disease, use of anticoagulants or antiplatelet medication, abnormal coagulation or thrombocytopenia, biliary obstruction, inflammatory bowel, symptomatic gallstones, celiac disease, ongoing use of medications known to cause or exacerbate symptoms of IBS and chronic, daily users of IBS medications.
- Use of scheduled IBS medications for 4 weeks prior to and during the treatment period.
Where it is running
- Kaiser Permanente — Los Angeles, California, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.