Mechanistic Pathways of Mindfulness Meditation in Post-traumatic Stress Disorder.
Completed · Not applicable
Conditions studied: Post-Traumatic Stress Disorders
In brief
The purpose of this study is to find out how meditation influences certain systems in the body: nervous system, hormonal system, and respiratory system. Another purpose is to see how meditation may help improve post-traumatic stress disorder symptoms.
Key facts
- Study ID
- NCT00778960
- Run by
- Oregon Health and Science University
- People needed
- 102
- Starts
- 2009-01-01
- Expected to finish
- 2014-05-01
- Last updated by the study team
- 2015-07-13
Who can join
Age: 25 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Combat veteran (defined by a score of ≥7 on the Combat exposure scale)
- Chronic PTSD diagnosis
- Age range (25-65 years)
- Both genders
- Good general medical health
- Stable dose of medications for concurrent stable medical conditions for at least 4 weeks prior to start of the study.
- Willing and able to provide informed consent.
You may not qualify if…
- Significant chronic medical illness including:
- current cancer treatment,
- unstable angina,
- recent myocardial infarction,
- current or past history of stroke,
- transient ischemic attack,
- congestive heart failure,
- chronic renal or hepatic failure,
- hypothyroidism
- Psychiatric or behavioral illness including:
- schizophrenia,
- schizoaffective disorder,
- bipolar disorder,
- psychotic disorder (not including transient dissociative states or flashbacks associated with PTSD re-experiencing symptoms),
- any DSM-IV cognitive disorder,
- current delirium,
- psychiatric instability or situational life crises, including evidence of being actively suicidal or homicidal, or any behavior which poses an immediate danger to the patient or others.
- Substance dependence disorder within 3 months of the study or
- current substance use other than alcohol (no more than 2 drinks/day by self-report)
- Sexual assault as primary PTSD event/s.
- Planning to move from the area in the next year.
- Prior or current meditation practice.
Where it is running
- Oregon Health and Science University — Portland, Oregon, United States
Full record on ClinicalTrials.gov
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