Mechanisms Underlying Impaired Diabetic Wound Healing

Recruiting now

Conditions studied: Non-healing Wound

In brief

The overall aim of this research is to utilize wound derived inflammatory cells from diabetic versus non diabetic human chronic wounds to understand mechanisms that are responsible for disregulated inflammation in individuals with diabetes. Biology of normal (peripheral blood derived cells) versus wound derived cells will also be studied.

Key facts

Study ID

NCT00777712

Run by

University of Pittsburgh

People needed

250

Starts

2008-09-01

Expected to finish

2030-12-31

Last updated by the study team

2026-06-05

Who can join

Age: 21 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Ages 21-80
• Chronic Wound (present >4 weeks)
• Diabetic \& Non-diabetic
• Adult surgical wounds

You may not qualify if…

• Inability to consent
• Pregnant women
• Therapeutically immunocompromised
• Individuals defined in 45 CFR 46 Subparts B,C, and D, nor from any other population considered vulnerable 2.9

Where it is running

• UPMC Montefiore — Pittsburgh, Pennsylvania, United States (enrolling)
• UPMC Presbyterian — Pittsburgh, Pennsylvania, United States (enrolling)

Full record on ClinicalTrials.gov

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