Detection of Ischemia in Asymptomatic Diabetics

Completed

Conditions studied: Type 2 Diabetes Mellitus

In brief

Asymptomatic subjects with Type 2 Diabetes Mellitus were randomized to either screening with Tc-99m sestamibi adenosine SPECT imaging or no screening. All patients will be followed for 5 years for the occurrence of cardiac death or non-fatal myocardial infarction. The aims are: 1. To prospectively assess the prevalence of silent myocardial ischemia in asymptomatic subjects with Type 2 Diabetes Mellitus. 2. To identify on the basis of clinical and/or biochemical variables in a high-risk cohort in which screening for coronary artery disease is appropriate. 3. To assess progression of (silent) myocardial ischemia after 3 years. 4. To assess the occurence of cardiac death or nonfatal myocardial infarction during 5 years follow-up in screened and not screened subjects.

Key facts

Study ID

NCT00769275

Run by

Yale University

People needed

1123

Starts

2000-08-01

Expected to finish

2008-01-01

Last updated by the study team

2008-10-09

Who can join

Age: 50 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 50-75 years
• Type 2 diabetes mellitus

You may not qualify if…

• Angina or anginal equivalent
• Abnormal rest ECG (Q or ST depression)
• Known CAD
• Stress testing within the last 3 years

Where it is running

• Yale University School of Medicine — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.