Ghrelin Changes After Roux-en-Y Gastric Bypass

Completed

Conditions studied: Obesity, Insulin Resistance

In brief

The purpose of this study is to determine whether gastric division (via Roux-en-Y gastric bypass) with resultant fundic isolation will alter the pattern(s) of Ghrelin secretion in the early post-operative period following feeding in morbidly obese subjects.

Key facts

Study ID

NCT00765596

Run by

Vanderbilt University

People needed

14

Starts

2005-01-01

Last updated by the study team

2011-11-17

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Serum creatinine and liver function tests < upper limits of normal
• Stable body weights for the past three months
• Women will have a negative pregnancy test
• patients who are already scheduled for RYGB with gastrostomy tube placement

You may not qualify if…

• Significant hepatic enzyme elevations (more than 100% of upper limits of normal)
• Serum creatinine > 1.5 mg/dl
• history of ketoacidosis or current metabolic acidosis
• current use of oral anticoagulants
• Positive pregnancy test (beta-human chorionic gonadotrophin) for females
• intercurrent infections
• patients with prior gastric operations

Where it is running

• Vanderbilt University Medical Center — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.