Bipolar Radiofrequency Ablation -Role in Prevention of Postoperative Atrial Fibrillation

Completed · Phase 4

Conditions studied: Postoperative Atrial Fibrillation

In brief

Atrial Fibrillation (AF) is one of the most common postoperative complications after coronary artery bypass grafting (CABG). Postoperative AF produces a substantial impact on hospital resources with an estimated annual expenditure of over $1 billion. This includes the cost of pharmacological treatment and the cost of the increased length of stay. The incidence of AF is about 30-40% in CABG patients and increases with age of the patient. As the average age of the patient that undergoes CABG surgery is increasing, it is critical to find a way to prevent or reduce the incidence of this complication. We propose a prospective, randomized, controlled study to determine the role of pulmonary vein isolation by bipolar ablation in the prevention or reduction of postoperative AF. The block- randomization plan will be used to maintain balance of the study and control arms throughout the study.

Key facts

Study ID

NCT00765089

Run by

University of Pittsburgh

People needed

35

Starts

2005-12-01

Expected to finish

2010-03-01

Last updated by the study team

2016-02-12

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients who require an isolated elective CABG surgery on CPB.
• Both male and female patients of age 18 years to 90 years.

You may not qualify if…

• Pre existing atrial fibrillation or history of previous atrial fibrillation.
• Inability to provide informed consent.
• Pregnant or nursing patients.
• Reoperative sternotomy
• Emergency CABG surgery.

Where it is running

• University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

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