The Efficacy of a Toothpaste to Reduce Sensitivity

Completed · Phase 3

Conditions studied: Dentin Hypersensitivity

In brief

Hypersensitivity

Key facts

Study ID

NCT00763269

Run by

Colgate Palmolive

People needed

626

Starts

2008-09-01

Expected to finish

2008-12-01

Last updated by the study team

2012-03-07

Who can join

Age: 12 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male and female subjects, ages: 12 years or older.
• Availability for the eight-week duration of the study.
• Two sensitive teeth, which must be anterior to the molars, and demonstrate cervical erosion/abrasion or gingival recession.
• Qualifying response to Tactile stimuli (Yeaple Probe) as defined by a score between 10-50 grams of force.
• Qualifying response to the Air Blast stimuli as defined by a score of 2 or 3 on the Schiff Cold Air Sensitivity Scale.
• Subjects need to satisfy the qualifying response to stimuli for both parameters assessed (Tactile or Air Blast) on at least two teeth to be entered into the study.
• Good general health with no known allergies to products being tested.
• Use of a non-desensitizing dentifrice for one month prior to entry into the study.
• Signed Informed Consent Form.

You may not qualify if…

• Gross oral pathology, chronic disease, or history of allergy to test products.
• Advanced periodontal disease or treatment for periodontal disease (including surgery) within the past twelve months.
• Sensitive teeth with a mobility greater than one.
• Teeth with extensive/defective restorations (including prosthetic crowns), suspected pulpitis, caries, cracked enamel, or used as abutments for removable partial dentures.
• Regular use of anticonvulsants, antihistamines, sedatives, tranquilizers, anti-inflammatory drugs, or analgesics.
• Participation in a desensitizing dentifrice study or regular use of a desensitizing dentifrice within the past one month.
• Current participation in any other clinical study.
• Allergies to triclosan, or oral care products, personal care consumer products, or their ingredients.
• Medical condition which prohibits not eating/drinking for 4 hours.

Where it is running

• Concordia Clinical Research — Cedar Knolls, New Jersey, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.