Metabolomic Profiling of Novel Mediators of Vascular Function

Stopped early

Conditions studied: Type 2 Diabetes Mellitus

In brief

The purpose of this study is to identify and characterize specific chemicals and metabolic pathways that change with forearm ischemia. These changes will be compared with forearm blood flow and flow-mediated vasodilation of the brachial artery.

Key facts

Study ID

NCT00762242

Run by

Brigham and Women's Hospital

People needed

48

Starts

2007-05-01

Expected to finish

2018-02-01

Last updated by the study team

2016-12-12

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Adults age 18 or older
• Type 2 diabetes mellitus

You may not qualify if…

• Type 1 diabetes mellitus
• Type 2 diabetics taking insulin, thiazolidinediones (rosiglitazone or pioglitazone), an amylin analog (Symlin [pramlintide]), or incretin mimetics (Byetta [exenatide])
• Pregnancy
• Uncontrolled hypertension, > 180/100 mmHg

Where it is running

• Brigham and Women's Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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