Evaluation of LDL Cholesterol in Patients Switched From 10 to 5 Milligrams of Zetia (Ezetimibe)
Completed · Not applicable
Conditions studied: Hypercholesterolemia
In brief
The purpose of this study is to compare the effect on LDL cholesterol levels of converting patients who are receiving the cholesterol absorption inhibitor Zetia at a dose of 10 milligrams to 5 milligrams, when prescribed as a split 10 milligram tablet.
Key facts
- Study ID
- NCT00762229
- Run by
- Bronx VA Medical Center
- People needed
- 39
- Starts
- 2007-07-01
- Expected to finish
- 2008-09-01
- Last updated by the study team
- 2013-06-14
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Subjects receiving ezetimibe 10 mg
- Subjects who have demonstrated compliance with ezetimibe as evidenced by the following Proportions of Days Covered patterns (which represent a PDC of more than 75%):
- 90 day prescriptions: Filled a ezetimibe prescription within the previous 4 months
- 60 day prescriptions: Filled a ezetimibe prescription within the previous 2.5 months
- 30 day prescriptions: Filled a ezetimibe prescription within the previous 1.5 months
- Patients willing and able to provide signed informed consent
You may not qualify if…
- Patients not receiving ezetimibe
- Patients receiving ezetimibe 5 milligrams
- Patients with a history of being titrated from ezetimibe 5 to 10 mg. Stroke,TIA, myocardial infarction, unstable angina, percutaneous coronary intervention, coronary artery bypass surgery, or major surgery within the 3 months
- Cancer undergoing active treatment
- Participation in any clinical study within the last 30 days
- Drug addiction or alcohol abuse within the past 6 months
- Patients unwilling or unable to provide informed consent
- Patients with poor compliance
- Women of childbearing potential
Where it is running
- Bronx VA Medical Center — The Bronx, New York, United States
Full record on ClinicalTrials.gov
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