A Study to Investigate the Anti-Plaque Effect of AN0128 Toothpaste

Completed · Phase 1

Conditions studied: Dental Plaque

In brief

The objective of this study was to evaluate the anti-plaque efficacy of the Anacor prototype dentrifice as compared to commercial control products following a single use of the dentrifice.

Key facts

Study ID

NCT00762151

Run by

Pfizer

People needed

18

Starts

2007-11-01

Expected to finish

2008-01-01

Last updated by the study team

2019-06-05

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Must be between ages 18 to 65 years inclusive
• Have a minimum of 16 natural uncrowned teeth (excluding 3rd molars) present
• Must give written informed consent
• Be in good general health
• Must discontinue oral hygiene for 24-hours after initial appointment
• No known history of allergy to personal care/consumer products or their ingredients, relevant to any ingredient in the test products as determined by the dental/medical professional monitoring the study

You may not qualify if…

• Medical condition which requires pre-medication prior to dental visits/procedures
• Advanced periodontal disease
• 5 or more decayed, untreated dental sites
• Diseases of the soft or hard oral tissues
• Orthodontic appliances
• Abnormal salivary function
• Use of drugs that can affect salivary flow
• Use of antibiotics one (1) month prior to or during this study
• Use of any over the counter medications other than analgesics (i.e. aspirin, ibuprofen, acetaminophen, naproxen), unless approved by the study medical staff
• Pregnant or breastfeeding
• Participation in another clinical study in the month preceding this study
• Allergic to common dentifrice ingredients
• Immune compromised individuals (HIV, AIDS, immuno suppressive drug therapy)
• History of allergic reaction to any anti-inflammatory agents

Where it is running

• Concordia Research Laboratories — Cedar Knolls, New Jersey, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.