Subgroups of Fibromyalgia Syndrome (FMS): Symptoms, Beliefs, and Tailored Treatment

Completed · Phase 2

Conditions studied: Fibromyalgia

In brief

Fibromyalgia syndrome (FMS) refers to a set of symptoms that include exhaustion, muscle pain, and tender points, where slight pressure can cause pain. Doctors do not know what causes FMS or how to cure it, but some treatments have helped relieve its symptoms. Progressive exercise, in which exercise is started at low levels and then increased, is one of the most reliable treatments, but people with FMS often avoid exercise or stop after completing exercise programs. This research will focus on the idea that people with FMS do not exercise because they are afraid of injury or have had a negative experience exercising. Participants will undergo one or a combination of several different treatments that aim to reduce fear of exercising. The different treatments will then be evaluated on their effectiveness in reducing disability among people with FMS.

Key facts

Study ID

NCT00762125

Run by

University of Washington

People needed

266

Starts

2005-12-01

Expected to finish

2012-01-01

Last updated by the study team

2014-12-02

Who can join

Age: 18 and older, up to 65. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Meet American College of Rheumatology (ACR) criteria for the diagnosis of fibromyalgia
• Able to comply with functional assessment and treadmill exercise

You may not qualify if…

• History of psychiatric hospitalization, suicide attempt, or significant problems with chemical dependency during the 6 months prior to enrollment in the study
• Evidence of severe psychiatric disorder that would prevent participation
• Medical conditions, such as significant cardiac disease, that make it medically unsuitable for participation in a progressive exercise program
• A medical condition, such as multiple sclerosis, that has a high likelihood of obscuring effects of the experimental treatments
• Anxiety or mood disorders in which symptoms are severe enough to prevent participation

Where it is running

• University of Washington — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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