Iron and the Breast-Fed Infant: Iron Status and Two Regimens of Iron Supplementation
Completed · Not applicable
Conditions studied: Iron Deficiency
In brief
Normal breastfed infants can develop iron deficiency by 6 months of age. This trial tested the hypothesis that regular provision of a source of iron beginning at 4 months of age improves iron status and could prevent iron deficiency. This was a prospective randomized trial involving breastfed infants. To be eligible, infants had to be predominantly breastfed (\<200 ml/day of formula) at 4 months of age. At 4 months infants were randomly assigned to one of two interventions or to control. The interventions consisted in the daily administration of medicinal iron in a dose of 7.5 mg (Medicinal Iron Group) or in the daily feeding of one jar of an iron-fortified cereal providing 7 mg of iron each day (Cereal Group). The control group received complementary foods chosen by he parents but no source of iron provided by the investigators. The interventions took place from 4 to 9 months. All infants were subsequently followed to 2 years of age.
Key facts
- Study ID
- NCT00760890
- Run by
- National Institutes of Health (NIH)
- People needed
- 171
- Starts
- 2001-06-01
- Expected to finish
- 2005-10-01
- Last updated by the study team
- 2008-09-26
Who can join
Age: 0 and older, up to 2. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Predominantly breastfed (at 4 months) term infants
You may not qualify if…
- Not predominantly breastfed at 4 months
- Premature infants
Where it is running
- Fomon Infant Nutrition Unit — Iowa City, Iowa, United States
Full record on ClinicalTrials.gov
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