Does Atorvastatin Prevent Post Operative Atrial Fibrillation After Pulmonary Resection: A Randomized Clinical Study

Completed · Not applicable · Has a placebo group

Conditions studied: Arrhythmia

In brief

The purpose of this study is to determine if atorvastatin (Lipitor) reduces the occurence of abnormal heart rhythm (atrial arrhythmia) following non cardiac thoracic surgery.

Key facts

Study ID

NCT00756886

Run by

University of Alabama at Birmingham

People needed

73

Starts

2008-09-01

Expected to finish

2011-05-01

Last updated by the study team

2013-04-02

Who can join

Age: 19 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients scheduled for elective non-cardiac thoracic surgery requiring thoracotomy for resection

You may not qualify if…

• Past medical history of pacemaker implantation
• Pregnancy or lactating
• History of Atrial arrhythmia within the past year
• Elevated liver enzymes pre-operatively
• Past medical history of any liver disease or history of liver transplantation
• Use of statins or any anti-arrhythmics (including beta-blockers, calcium channel blockers, digoxin) within 3 months prior to surgery
• Pre-op EKG showing atrial arrhythmia

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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