The Acute Cardiovascular Effects of Marathon Running Using Magnetic Resonance Imaging

Completed

Conditions studied: Myocardial Ischemia, Left Ventricular Systolic Dysfunction, Elevated Cardiac Enzymes

In brief

Using blood testing and cardiac magnetic resonance imaging (MRI), the investigators aim to determine if there are necrotic areas of myocardium in participants who complete a marathon. In addition, the investigators aim to describe the acute and chronic structural abnormalities that occur as a result of endurance training. The study hypothesis is that myocardial necrosis is present in runners completing a marathon competition.

Key facts

Study ID

NCT00752752

Run by

Corewell Health East

People needed

25

Starts

2008-09-01

Expected to finish

2010-05-01

Last updated by the study team

2012-04-03

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Detroit Free Press Marathon participant on October 19, 2008,
• Age > 18 years old,
• Ability to provide informed consent.

You may not qualify if…

• Known coronary or structural heart disease
• Pregnancy,
• Extreme claustrophobia,
• Metal implants,
• Renal dysfunction.

Where it is running

• William Beaumont Hospital — Royal Oak, Michigan, United States

Full record on ClinicalTrials.gov

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