Intravenous Terbutaline in Severe Status Asthmaticus

Status unconfirmed

Conditions studied: Status Asthmaticus

In brief

Terbutaline is a medication that is used to treat serious asthma attacks (status asthmaticus). The purpose of this study is to determine if terbutaline is effective and safe when given as a continuous intravenous infusion to children ages 2 years to 18 years of age. Children participating in this study are inpatients in the Intensive Care Unit with a diagnosis of status asthmaticus and are receiving terbutaline as part of their routine care. Blood samples and physiological assessments will be used to determine how the body is using terbutaline and how well it is working.

Key facts

Study ID

NCT00750568

Run by

Wayne State University

People needed

36

Starts

2007-10-01

Expected to finish

2009-08-01

Last updated by the study team

2008-09-10

Who can join

Age: 2 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Children 2 to 18 years of age.
• Admission to the ICU with a diagnosis of status asthmaticus.
• The pediatric intensivist taking care of the patient has decided to initiate intravenous terbutaline therapy.
• An indwelling venous catheter or arterial catheter that was placed for routine ICU monitoring.
• Informed consent obtained from the patient's parents or legal guardian.

You may not qualify if…

• Existing cardiovascular disease.
• History of bronchopulmonary dysplasia.
• Prior inclusion in this study.
• Known hypersensitivity to terbutaline, or prior adverse event associated with terbutaline.
• Terbutaline use within 48 hours of initiation of the study.

Where it is running

• Kosair Children's Hospital — Louisville, Kentucky, United States
• Children's Hospital of Michigan — Detroit, Michigan, United States
• Rainbow Babies and Childrens' Hospital — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.