Urine Concentration of S100B in Extremely Premature Infants

Completed

Conditions studied: Premature Infants

In brief

S100B, a calcium-binding protein, is found predominantly in the central nervous system (CNS) and is increased in CSF and blood after CNS injury. There are two objectives to this study. Is urine S100B concentration correlated with the serum concentration of S100B in infants born at 29-36 weeks gestation. The presence and severity of intracranial pathology on S100B concentration will be investigated. Further analysis will demonstrate if birth weight, daily fluid intake, urine output, and urine creatinine influence this relationship.

Key facts

Study ID

NCT00747591

Run by

University of Utah

People needed

68

Starts

2002-11-01

Expected to finish

2005-04-01

Last updated by the study team

2010-07-23

Who can join

Age: any, up to 0. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Preterm infants born at <28 weeks gestation will be eligible for enrollment in this study.

You may not qualify if…

• Infants with fetal malformations, chromosomal anomalies, and clinically significant sepsis (retractable hypotension, neutropenia, and thrombocytopenia) will be excluded, other.

Where it is running

• University of Utah — Salt Lake City, Utah, United States

Full record on ClinicalTrials.gov

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