Efficacy of Esomeprazole for Non-Allergic Rhinitis: A Double-blind, Placebo Controlled Trial

Completed · Not applicable · Has a placebo group

Conditions studied: Vasomotor Rhinitis

In brief

The purpose of this study was to see if high dose esomeprazole (40mg bid) was effective in treating non-allergic rhinitis

Key facts

Study ID

NCT00745849

Run by

University of Texas Southwestern Medical Center

People needed

43

Starts

2005-06-01

Expected to finish

2008-03-01

Last updated by the study team

2019-06-11

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• age between 18-80, symptoms of perennial rhinitis, negative epicutaneous skin testing to a panel of common aeroallergens, and ability to speak English

You may not qualify if…

• pregnancy or breast-feeding, evidence of positive skin tests to a common aeroallergen, treatment with a proton pump inhibitor within the month prior to enrollment, treatment with any other anti-reflux therapy within the last month on a daily basis or within the last two weeks on an as needed basis, and other gastrointestinal disorders leading to reflux symptoms

Where it is running

• Clinical Trials Office, Aston Building, UT Southwestern — Dallas, Texas, United States

Full record on ClinicalTrials.gov

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