Use of MRI and PET for Assessing Disease Activity in Takayasu's Arteritis

Completed

Conditions studied: Takayasu Arteritis

In brief

Assessing disease activity in people with Takayasu's arteritis is difficult, as most people with the disease do not exhibit visible, measurable symptoms. Combination positron emission tomography/computed axial tomography (PET/CT) is a particularly sensitive, accurate scanning method that may improve researchers' ability to evaluate people with the disease. This study will determine the effectiveness of PET/CT in assessing disease activity in people with Takayasu's arteritis.

Key facts

Study ID

NCT00744952

Run by

Peter Merkel

People needed

26

Starts

2008-08-01

Expected to finish

2018-09-30

Last updated by the study team

2018-10-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of Takayasu's arteritis, as defined by the VCRC Longitudinal Study #5503
• Currently enrolled in the VCRC Longitudinal Study #5503
• Active disease has occurred in conjunction with a disease relapse within 2 weeks before study entry (A detailed definition of "active disease" is available in the study protocol.)
• Willing and able to comply with the schedule for imaging studies and follow-up procedures

You may not qualify if…

• Pregnant or breastfeeding
• Unable to comply with study guidelines
• Unable to safely undergo MRI scanning

Where it is running

• Boston University School of Medicine — Boston, Massachusetts, United States
• Mayo Clinic — Rochester, Minnesota, United States
• Cleveland Clinic Foundation — Cleveland, Ohio, United States
• St. Joseph's Healthcare — Hamilton, Ontario, Canada
• Mount Sinai Hospital, Toronto — Toronto, Ontario, Canada

Full record on ClinicalTrials.gov

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