Doxorubicin Hydrochloride Liposome, Bortezomib, and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma
Status unconfirmed · Phase 2
Conditions studied: Multiple Myeloma and Plasma Cell Neoplasm
In brief
RATIONALE: Drugs used in chemotherapy, such as doxorubicin hydrochloride liposome and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Giving bortezomib together with combination chemotherapy may kill more cancer cells. PURPOSE: This phase II trial is studying how well giving doxorubicin hydrochloride liposome together with bortezomib and dexamethasone works in treating patients with newly diagnosed multiple myeloma.
Key facts
- Study ID
- NCT00742404
- Run by
- Oncotherapeutics
- People needed
- 35
- Starts
- 2008-07-01
- Last updated by the study team
- 2013-12-18
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Arizona Clinical Research Center, Incorporated — Tucson, Arizona, United States
- Comprehensive Blood and Cancer Center — Bakersfield, California, United States
- San Diego Pacific Oncology and Hematology Associates, Incorporated - Escondido — Escondido, California, United States
- Loma Linda University Cancer Institute at Loma Linda University Medical Center — Loma Linda, California, United States
- Oncology Care Medical Associates - San Gabriel — Los Angeles, California, United States
- Desert Cancer Care — Rancho Mirage, California, United States
- Sutter Cancer Center at Roseville Medical Center — Roseville, California, United States
- Santa Barbara Hematology Oncology Medical Group at Cancer Center of Santa Barbara — Santa Barbara, California, United States
- James R. Berenson MD, Incorporated — West Hollywood, California, United States
- Center for Cancer and Blood Disorders — Bethesda, Maryland, United States
- New York Medical College — Valhalla, New York, United States
- Charleston Hematology Oncology Associates, PA — Charleston, South Carolina, United States
Full record on ClinicalTrials.gov
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