Duragen Versus Duraguard in Chiari Surgery

Completed · Phase 3

Conditions studied: Chiari Malformation

In brief

The study evaluates two materials used for duraplasty of the posterior cranial fossa in treatment of Chiari malformation. One material (DuraGen) is a non-suturable collagen matrix that is applied over the defect if brain coverings (dura); the other (DuraGuard) is made out of bovine pericardium and has to be sutured during application. The study compares these two materials used for duraplasty of patients undergoing Chiari surgery in a prospective randomized fashion to check the rate of surgical complications associated with each material, patient's outcomes, length of surgery and the hospital stay, etc.

Key facts

Study ID

NCT00741858

Run by

University of Illinois at Chicago

People needed

34

Starts

2003-04-01

Expected to finish

2010-04-01

Last updated by the study team

2015-07-13

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Symptomatic Chiari malformation

You may not qualify if…

• Presence of ventriculoperitoneal shunt
• Pregnancy

Where it is running

• University of Illinois Medical Center in Chicago — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.