Effectiveness of Three Different Psychotherapies for Chronic Post-Traumatic Stress Disorder

Completed · Not applicable

Conditions studied: Post-Traumatic Stress Disorder

In brief

This study will examine whether interpersonal psychotherapy is as effective in treating post-traumatic stress disorder as the established therapies of prolonged exposure and relaxation.

Key facts

Study ID

NCT00739765

Run by

New York State Psychiatric Institute

People needed

110

Starts

2008-04-01

Expected to finish

2014-03-01

Last updated by the study team

2026-05-12

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Meets DSM-IV (Diagnostic and Statistical Manual of Mental Disorders) criteria for primary, chronic PTSD
• At least moderately severe symptoms, defined by a minimum total (frequency plus severity) Clinician-Administered PTSD Scale score greater than 50
• Willing to undergo an independent clinical assessment and other ratings

You may not qualify if…

• Diagnosis of schizophrenia, bipolar disorder, or other psychotic disorders
• Psychiatric disorder due to a general medical condition
• Current substance abuse or dependence
• Acute suicide or homicide risk
• Unstable or life-threatening medical condition
• Primary diagnosis of borderline personality disorder, major depressive disorder, or major depression, melancholic subtype
• Diagnosis of antisocial personality disorder
• At least partial benefit from current treatment regimen
• Unwillingness to discontinue current ineffective psycho- or pharmacotherapy
• Inability to speak or read English

Where it is running

• New York State Psychiatric Institute — New York, New York, United States

Full record on ClinicalTrials.gov

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