Study Evaluating PAZ-417 in Cerebrospinal Fluid in Subjects With Alzheimer's Disease

Stopped early · Phase 1 · Has a placebo group

Conditions studied: Alzheimer Disease

In brief

The primary purpose of this study is to assess biomarker known as amyloid beta peptide 40 (Ab40) in Cerebrospinal Fluid (CSF), following a single oral dose of PAZ-417 in subjects with Alzheimer Disease (AD). This study will also consider another biomarker amyloid beta peptide 42 (Ab42) in Cerebrospinal Fluid in subjects with Alzheimer Disease and assess the safety, tolerability and pharmacokinetic profile of PAZ-417 in both plasma and Cerebrospinal Fluid in these subjects.

Key facts

Study ID
NCT00739037
Run by
Wyeth is now a wholly owned subsidiary of Pfizer
People needed
10
Starts
2008-08-01
Expected to finish
2008-12-01
Last updated by the study team
2009-08-04

Who can join

Age: 55 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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