Inhaled Nitric Oxide by Oxygen Hood in Neonates

Completed · Phase 4 · Has a placebo group

Conditions studied: Respiratory Failure, Infant, Persistent Fetal Circulation

In brief

Inhaled nitric oxide (iNO) improves oxygenation in term infants with respiratory failure. However, iNO has been primarily used in infants receiving mechanical ventilation. This study is a pilot study to determine if iNO given into an oxygen hood is effective in improving oxygenation in term and near-term infants who have poor oxygenation but who are not yet mechanically ventilated.

Key facts

Study ID

NCT00732537

Run by

University of Alabama at Birmingham

People needed

8

Starts

1999-03-01

Expected to finish

2005-06-01

Last updated by the study team

2008-08-12

Who can join

Age: any, up to 0. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• gestation >34 weeks at birth
• age <7 days
• post-ductal arterial line
• an A-aDO2 of 400 to 600 on two blood gases, at least 30 minutes apart.

You may not qualify if…

• Infants with major malformations
• Infants with cardiac disease

Where it is running

• Regional Neonatal ICU, University of Alabama at Birmingham — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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