Pharmacogenetic Determinants Of Treatment Response In Children

Recruiting now

Conditions studied: All Malignancies, Children Being Treated for Catastrophic Illness

In brief

To investigate whether genetic polymorphisms in genes encoding proteins involved in the metabolism or effects of drugs or environmental agents influence the disposition or effects of these xenobiotic substrates. To investigate the nature of heritability and the genetic basis of pharmacogenetic traits by studying family members of individuals with specific genotypes.

Key facts

Study ID

NCT00730678

Run by

St. Jude Children's Research Hospital

People needed

8800

Starts

1998-08-17

Expected to finish

2034-03-01

Last updated by the study team

2026-04-29

Who can join

Age: any. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Any patients under evaluation/treatment at St. Jude Children's Research Hospital (SJCRH)
• Parents or family members of St. Jude patients
• Non patient volunteers
• All study subjects must provide informed consent for participation
• Assent/Consent of the patient (parent) must be provided prior to attempts made by investigators to enroll a family member of a SJCRH patient

Where it is running

• St. Jude Children's Research Hospital — Memphis, Tennessee, United States (enrolling)

Full record on ClinicalTrials.gov

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