Peripherally Inserted Central Catheter (PICC) Thrombosis: Reverse Taper Versus Non-tapered Catheters
Completed · Not applicable
Conditions studied: Venous Thrombosis
In brief
The purpose of this study is to compare two different marketed PICC (peripherally inserted central catheter) designs. Clotting rates, procedural bleeding and ease of catheter insertion will be compared. It is hypothesized that the non-tapered design has a lower clotting rate and is easier to place than the tapered design. Bleeding rates are expected to be about the same.
Key facts
- Study ID
- NCT00728819
- Run by
- University of Pennsylvania
- People needed
- 339
- Starts
- 2008-08-01
- Expected to finish
- 2011-08-01
- Last updated by the study team
- 2018-04-27
Who can join
Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- All inpatients, age 18 to 90, in need of de novo central venous access with a double lumen catheter indication of > 2 weeks
- Informed consent and HIPAA consent forms discussed and signed by patient or their authorized representative
You may not qualify if…
- Skin related problems around the insertion site (infection, phlebitis, scars)
- History of mastectomy/axillary dissection on insertion side
- Coagulopathy with an INR of > 2.0
- Thrombocytopenia with platelets < 25,000 uL
- Renal insufficiency with a creatinine of > 3.0 mg/dL
- Documented current upper extremity or central venous thrombosis
- Hypercoagulable states (protein C or S deficiency, AT-III deficiency, lupus anticoagulant)
- Catheters needed for therapy within less than an hour (emergent placement not allowing sufficient time for proper research consent and randomization)
- Patient has already been enrolled in this research study
- Life expectancy less than 1 month
Where it is running
- Hospital of the University of Pennsylvania — Philadelphia, Pennsylvania, United States
Full record on ClinicalTrials.gov
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