Comparison of Coronary CT Angiography With Conventional Coronary Angiography in Liver and Lung Transplant Candidates
Withdrawn before enrolling
Conditions studied: Coronary Artery Disease
In brief
The overall goal of this study is to determine if non-invasive imaging with state of the art CT coronary angiography can be used to screen for coronary artery disease in high risk patients prior to liver and lung transplantation. The current protocol for coronary artery disease assessment at UCSF before liver and lung transplantation involves screening with stress tests and/or coronary angiograms in patients with increased risk of coronary artery disease. Coronary angiogram will be used as gold standard for assessment of coronary CTA accuracy.
Key facts
- Study ID
- NCT00727051
- Run by
- University of California, San Francisco
- People needed
- 0
- Starts
- 2007-06-01
- Expected to finish
- 2014-07-01
- Last updated by the study team
- 2019-07-22
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Liver transplant candidates referred for invasive coronary angiography which include:
- Patients with suspicious symptoms for CAD or;
- Asymptomatic patients;
- Abnormal non-invasive testing or 1 major risk factor for coronary artery disease or LVEF < 60% on echo.
- Lung transplant candidates referred for invasive coronary angiography which include:
- Patients with suspicious symptoms for CAD or;
- Asymptomatic patients;
- Abnormal non-invasive testing or 1 major risk factor for coronary artery disease or LVEF < 60% on echo in patients with low SVR (typical for ESLD).
- Any ethnic background is acceptable.
You may not qualify if…
- Patients with contraindications for the use of iodinated contrast (allergic reaction, renal failure, multiple myeloma, etc) will be excluded.
- Children and pregnant women will be excluded because of risks associated with radiation exposure.
- Patients must have no atrial fibrillation, as this will interfere with cardiac gating for the examination.
- Patients unable to give informed consent will be excluded as well.
Where it is running
- UCSF Medical Center — San Francisco, California, United States
Full record on ClinicalTrials.gov
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