Admixture Mapping of Ethnic and Racial Insulin Complex Outcomes

Completed

Conditions studied: Healthy

In brief

The main objective of this study is to investigate the effect of genetic and environmental parameters on racial/ethnic differences in aspects of insulin secretion and action. The genetic component will be modeled by estimating the degree of European genetic admixture (ADM) obtained from approximately 50 ancestry informative markers (AIMs). The environmental components will be modeled by measuring energy intake (food intake), energy expenditure (physical activity) and socioeconomic status.

Key facts

Study ID

NCT00726778

Run by

University of Alabama at Birmingham

People needed

360

Starts

2004-05-01

Expected to finish

2010-12-01

Last updated by the study team

2011-03-16

Who can join

Age: 7 and older, up to 12. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• African American, European American, or Hispanic American, aged 7-12, healthy, weight is equal to or greater than 25 Kg

You may not qualify if…

• Type 1 or 2 diabetes, polycystic ovary disease, disturbances in glucose or lipid metabolism disturbances
• Use of medication known to affect body composition or physical activity, diagnosis of genetic disorders known to affect body composition or fat distribution
• Use of tobacco, alcohol consumption in excess of 400 g per week
• Menstruated for more than a year prior to the recruitment; OR
• A medical history that counter-indicates inclusion of the study

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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