Pre-emptive Hemodynamic Optimization of High Risk Patients Undergoing Elective Major Surgical Procedures

Withdrawn before enrolling · Not applicable

Conditions studied: Hemorrhage

In brief

Several recent clinical trials have documented that early aggressive resuscitation approached guided by defined hemodynamic variables using thoughtful protocols may improve outcome. The concept underscored by this newer trial was that appropriate resuscitation prevents subsequent tissue injury even if overt shock is present, if the resuscitation is carried out early enough.

Key facts

Study ID

NCT00725972

Run by

University of Pittsburgh

People needed

0

Starts

2008-07-01

Last updated by the study team

2017-08-01

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult, Male or female.
• Patients undergoing elective major surgery.
• Patients with normal renal function.
• All patients will sign informed consent.

You may not qualify if…

• Major organ failure.
• Low cardiac output conditions.
• Pulmonary hypertension.
• Severe pulmonary disease.
• Patient refusal to participate in the study.
• Pregnancy.
• Emergency Surgery.
• Lithium allergy or patient on lithium.

Where it is running

• UPMC-Presbyterian Hospital — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

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