FFA Hypertension and Inflammation in Lean and Obese Subjects

Completed · Not applicable

Conditions studied: Diabetes, Hypertension, Obesity

In brief

Although a large number of obese patients develop high blood pressure, the cause is unknown. The purpose of this study is to look at the effect of high fatty acids (a type of fat) in the development of high blood pressure in obese people.

Key facts

Study ID

NCT00721617

Run by

Emory University

People needed

12

Starts

2009-04-01

Expected to finish

2011-06-01

Last updated by the study team

2015-07-27

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Males or females
• Obese subjects (body mass index (BMI) ≥ 30 kg/m\^2)
• 18 and 65 years
• Blood pressure reading < 140/80 mm Hg and no prior history of hypertension

You may not qualify if…

• History of diabetes mellitus
• History of hypertension
• Fasting triglyceride levels > 250 mg/dL
• Liver disease (ALT 2.5x > upper limit of normal)
• Serum creatinine ≥1.5 mg/dL
• Smokers, drug or alcohol abuse
• Mental condition rendering the subject unable to understand the scope and possible consequences of the study
• Female subjects who are pregnant or breast feeding

Where it is running

• Grady Memorial Hospital — Atlanta, Georgia, United States

Full record on ClinicalTrials.gov

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