Adult Growth Hormone Deficiency and Cardiovascular Risk

Stopped early · Phase 4

Conditions studied: Growth Hormone Deficiency

In brief

This protocol will assess the cardiovascular risk associated with growth hormone deficiency in adults. We will use multiple modalities to assess risk for heart attacks or strokes including blood work, ultrasound, MRI and endothelial cell biopsies in both patients who are growth hormone deficient and in patients with normal growth hormone secretion. We hypothesize that adults with growth hormone deficiency will have results suggestive of an increased risk for cardiovascular disease.

Key facts

Study ID

NCT00720902

Run by

Columbia University

People needed

7

Starts

2007-02-01

Expected to finish

2011-05-01

Last updated by the study team

2022-11-16

Who can join

Age: 19 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults 19 years or older who have undergone transsphenoidal surgery for a clinically non-secreting pituitary adenoma

You may not qualify if…

• Currently taking growth hormone, radiation therapy in the past 5 years, changes in dose of other pituitary hormone replacement therapy in past 3 months, taking hydrocortisone (or its equivalent) at a dose of > 30 mg/day, pregnant or nursing women

Where it is running

• Columbia University, College of Physicians and Surgeons — New York, New York, United States

Full record on ClinicalTrials.gov

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