Efficacy of Losartan in Preventing Progression of COPD

Completed · Phase 4 · Has a placebo group

Conditions studied: COPD, Emphysema, Chronic Bronchitis, Smoking

In brief

Evidence in animals shows that losartan can prevent or reverse inflammation and lung damage due to smoking. The goal of this study is to determine whether this drug which is also used to treat hypertension can stabilize or improve lung function in people who have from chronic obstructive pulmonary disease (COPD).

Key facts

Study ID

NCT00720226

Run by

Johns Hopkins University

People needed

106

Starts

2008-07-01

Expected to finish

2016-08-01

Last updated by the study team

2017-04-25

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults with COPD who are either active or former smokers

You may not qualify if…

• Clinical requirement or history of intolerance of angiotensin receptor blockers, serious heart, liver, kidney, neurological disease.

Where it is running

• Johns Hopkins Asthma and Allergy Center — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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