Addition of Nitrous Oxide and Its Effects on Depth of Anesthesia

Completed · Not applicable

Conditions studied: Deep Sedation, Anesthesia, General

In brief

The study hypothesizes that adding 60% nitrous oxide to a steady state sevoflurance or propofol anesthetic will lead to a decrease in both BIS and Entropy indices during a constant level of surgical stimulus

Key facts

Study ID

NCT00717574

Run by

University of Oklahoma

People needed

32

Starts

2008-03-01

Expected to finish

2010-10-01

Last updated by the study team

2017-07-31

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Ages 18 to 55yrs
• ASA status less than and equal to 2

You may not qualify if…

• Surgery on head and neck
• ASA greater than 3
• Contraindication to nitrous oxide
• Pregnant women
• History of dementia and stroke, or other organic brain disorder
• Prisoner
• Ear surgery

Where it is running

• University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States

Full record on ClinicalTrials.gov

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