The Effect of TRA-8 on Ovarian Cancer Tissue

Completed

Conditions studied: Ovarian Cancer

In brief

The goal of this study is to determine the apoptosis-inducing efficacy of TRA-8 in patient ovarian cancer tissues using a tissue slice technology. In addition, we want to evaluate the expression of apoptosis regulatory proteins using multiplex proteomic technology and its correlation with TRA-8-induced cytotoxicity in patient ovarian cancer tissues.

Key facts

Study ID

NCT00711932

Run by

University of Alabama at Birmingham

People needed

478

Starts

2008-08-01

Expected to finish

2013-01-01

Last updated by the study team

2013-09-11

Who can join

Age: 19 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Patients must have suspected ovarian cancer and must be a candidate for surgery.
• Patients must have provided a signed consent form.
• Patients must have extra tumor at the time of surgery that is appropriate for tumor slicing.
• Patients must be at least 19 years of age.
• Patients must have histologically confirmed epithelial carcinoma of the ovary or of extra-ovarian origin, any histologic subtype or stage.

You may not qualify if…

• Patients who have received any prior therapy for ovarian cancer.

Where it is running

• University of Alabama — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.