Effectiveness of Minimally Invasive Total Knee Replacement in Improving Rehabilitation and Function

Completed · Phase 2

Conditions studied: Osteoarthritis

In brief

Osteoarthritis (OA) is a long-term degenerative joint disease that disables about 10% of people over the age of 60 and compromises the quality of life of more than 20 million Americans. A procedure called total knee arthroplasty (TKA), in which the affected surface of the knee joint is replaced by plastic or metal, has been successful in restoring comfort and mobility to formerly arthritic joints. This study will compare quadriceps muscle strength, knee range of motion, and pain in people who have had a traditional TKA with those who have had a minimally invasive TKA.

Key facts

Study ID: NCT00710840
Run by: University of Colorado, Denver
People needed: 44
Starts: 2008-06-01
Expected to finish: 2012-01-01
Last updated by the study team: 2015-06-10

Who can join

Age: 50 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Diagnosis of osteoarthritis
Eligible for a unilateral or bilateral primary TKA to be performed by Dr. Michael Dayton (University of Colorado Hospital)
Minimum of 110 degrees of active knee flexion
No greater than 10 degrees of anatomic knee varus, 15 degrees anatomic valgus, and 10 degrees flexion contracture
Body mass index less ≤ 40 kg/m2

You may not qualify if…

Any brain, circulation, or heart problems that limit function
Severe osteoarthritis or other orthopedic conditions that limit function in the lower extremity that is not undergoing the TKA

Where it is running

University of Colorado Health Sciences Center — Boulder, Colorado, United States
National Jewish Medical and Research Center — Denver, Colorado, United States
University of Colorado Health Sciences Center — Denver, Colorado, United States

Full record on ClinicalTrials.gov

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