The Human Immunodeficiency Virus and Osteopathic Manipulation Evaluation Study

Completed · Not applicable

Conditions studied: HIV Infections

In brief

Treatment options that increase immune function, such as Osteopathic Manipulation Treatment (OMT) lymphatic techniques, may provide improved short or long term performance of the immune system. However, the efficacy of OMT to boost immune function among people living with HIV has not yet been examined in a controlled study. Our experiment is designed to examine the short (45 minutes) term impact of OMT on the white blood cells counts of HIV positive men who are either antiretroviral therapy (ART) naïve or have not taken ART for at least 12 months prior to enrollment in the study.

Key facts

Study ID

NCT00703248

Run by

Nova Southeastern University

Starts

2007-10-01

Expected to finish

2008-06-01

Last updated by the study team

2008-07-08

Who can join

Age: 18 and older, up to 65. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• are either Antiretroviral Therapy (ART) naïve or not have taken ART for the past 12 months
• are between the ages of 18 to 65
• have a CD4+ T cell count between 200-700cells/mm3
• have viral loads less than 100,000 copies/mL
• do not have any medical condition that limits his ability to participate in this study as defined by his physician (e.g., cancer, blood clotting disorder etc.)
• are willing to provide informed consent
• are not using any drugs recreationally
• are not on prescribed systemic steroids
• are willing to recruit a friend/partner, aware of the their HIV serostatus, to be trained in OMT techniques and apply it to him daily.

You may not qualify if…

• history of malignancy excluding both squamous cell carcinoma and basal cell carcinoma of the skin and/or any malignancies fully treated and considered cured by the treating physician for at least 1 year
• aortic aneurism/disease
• vertebral artery disease
• carotid artery stenosis/disease
• abdominal hernias
• portal hypertension
• cirrhosis
• cervical disc disease currently exhibiting radicular symptomatology (i.e. numbness, burning, muscle weakness, etc)
• infectious mononucleosis in the past 12 weeks,
• pneumothorax
• bone disease
• Participants with a medical access port and/or a noncompliant ribcage will be excluded from the study.
• The potential causes for ribcage noncompliance include:
• congestive obstructive pulmonary disorder (COPD)
• spinal arthritis
• costochondritis
• congestive heart failure (CHF)
• pulmonary edema
• recent trauma to the ribcage
• certain connective tissue disease such as Ankylosing Spondylitis
• There is a risk of abdominal aortic aneurysm (AAA) rupture in participants with AAA and these participants are excluded from the study.

Where it is running

• Nova Southeastern University — Fort Lauderdale, Florida, United States

Full record on ClinicalTrials.gov

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