The Prevalence of Sleep Disordered Breathing in Hospitalized Patients With Acutely Decompensated Heart Failure Syndrome

Completed

Conditions studied: Sleep Apnea, Congestive Heart Failure, Heart Failure

In brief

OSA is associated with large negative swings in the intrathoracic pressure, significant increase in the sympathetic nerve activity and repetitive surges in blood pressure, along with episodic hypoxia and hypercapnea (8,9). These autonomic and respiratory changes may increase the cardiac muscle workload, cardiac dysrrhythmia, and exacerbate ischemia (10,11,12). Treatment with CPAP is the most successful therapeutic modality available for OSA. It is still not clear whether establishing the diagnosis of OSA and initiating treatment with CPAP while still in the hospital carries any benefit in the management of patients with acute heart failure. This study will evaluate the effect of work up and treatment of OSA on the outcome of patients hospitalized with acute CHF.

Key facts

Study ID

NCT00701519

Run by

Ohio State University

People needed

1600

Starts

2007-06-01

Expected to finish

2013-10-01

Last updated by the study team

2017-01-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• OSU Heart Failure Patient
• Able to Complete Survey

You may not qualify if…

• Neurological Deficit
• No Heart failure
• Less than 18 yrs old

Where it is running

• The Ohios State University — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

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