Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea

Recruiting now · Phase 2

Conditions studied: Sleep Apnea, Obstructive

In brief

Prospective, interventional cohort study of drug-induced sleep endoscopy (DISE) to evaluate the upper airway in a cohort of obstructive sleep apnea (OSA) surgical patients. This study has investigated the reliability of this technique, demonstrating moderate-substantial interrater and test-retest reliability. This research has also compared DISE findings to those of the lateral cephalogram X-ray and examined DISE findings in individuals who have not responded to previous sleep apnea surgery. These papers have been published and available through PubMed. Additional research is ongoing, with examination of DISE findings, comparison to other evaluation techniques, and the association between DISE findings and surgical outcomes.

Key facts

Study ID

NCT00695214

Run by

University of California, Los Angeles

People needed

800

Starts

2004-02-01

Expected to finish

2035-06-01

Last updated by the study team

2026-07-01

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients with OSA considering surgical treatment

You may not qualify if…

• Minors
• Pregnant women
• Patients unable to provide informed consent in English themselves
• Prisoners
• Allergy to propofol, soybean oil, egg lecithin or glycerol
• Other contraindication to use of propofol (decision of anesthesiologist or otolaryngologist.)

Where it is running

• UCLA Santa Monica Medical Center — Santa Monica, California, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.