Randomized Clinical Trial of Intensive Computer-based Cognitive Remediation in Recent-onset Schizophrenia

Completed · Phase 1/Phase 2

Conditions studied: Schizophrenia

In brief

The aim of this study is to investigate the efficacy of neuroscience-guided computerized cognitive training exercises on the remediation of cognitive deficits and symptoms associated with recent-onset schizophrenia and to examine the influence of subject characteristics, brain structure and function, and pharmacotherapy on the response to remediation.

Key facts

Study ID

NCT00694889

Run by

University of California, San Francisco

People needed

144

Starts

2007-08-01

Expected to finish

2015-02-01

Last updated by the study team

2016-05-16

Who can join

Age: 12 and older, up to 35. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Clinical diagnosis of schizophrenia, schizophreniform, or schizoaffective disorder
• First psychotic episode within the last 3 years
• Good general physical health
• Age between 12-35
• Is fluent and proficient in the English language
• Achieved clinical stability (e.g., outpatient status for at least 3 months before study entry; on stable doses of medication for at least 1 month before study entry
• Minors must have parental/legal guardian consent to participate

You may not qualify if…

• Any neurological disorder
• History of psychoactive substance abuse in the past 6 months

Where it is running

• University of California, Davis — Sacramento, California, United States
• University of California, San Francisco — San Francisco, California, United States

Full record on ClinicalTrials.gov

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