Blind Elderly Melatonin Treatment Study

Stopped early · Not applicable

Conditions studied: Blindness

In brief

The primary focus of this five-year study will be to optimize the melatonin dosing regimen for synchronizing the body clocks of elderly blind individuals to the 24-hour day.

Key facts

Study ID

NCT00692094

Run by

Oregon Health and Science University

People needed

12

Starts

2004-08-01

Expected to finish

2008-12-01

Last updated by the study team

2019-11-27

Who can join

Age: 55 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults 55-100 years old
• Blindness for at least one year, verified by an ophthalmologic exam
• Ability to comply with the requirements of the experimental protocol
• No clinically significant abnormalities (other than blindness) on a general physical examination
• Subjects must be competent to sign informed consent

You may not qualify if…

• Abnormal heart, liver or kidney function; a current Axis I psychiatric or substance abuse disorder according to the DSM-IV Manual
• A diagnosis of obstructive sleep apnea (apnea index > 10) or nocturnal myoclonus (> 10 associated arousals/hour)
• External demands that limit the ability to maintain a regular schedule, e.g., night shift work

Where it is running

• Sleep and Mood Disorders Lab, Oregon Health & Science University — Portland, Oregon, United States

Full record on ClinicalTrials.gov

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