Pemetrexed and Cisplatin in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer
Completed · Phase 2
Conditions studied: Cervical Cancer
In brief
RATIONALE: Pemetrexed may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving pemetrexed together with cisplatin may kill more tumor cells. PURPOSE: This phase II trial is studying the side effects of giving pemetrexed together with cisplatin and to see how well it works in treating patients with advanced, persistent, or recurrent cervical cancer.
Key facts
- Study ID
- NCT00691301
- Run by
- Gynecologic Oncology Group
- People needed
- 55
- Starts
- 2008-09-01
- Expected to finish
- 2014-07-01
- Last updated by the study team
- 2018-01-09
Who can join
Age: any, up to 120. Sex: female. Healthy volunteers: not accepted.
Where it is running
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
- Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center — Orange, California, United States
- University of Mississippi Cancer Clinic — Jackson, Mississippi, United States
- Women's Cancer Center - La Canada — Las Vegas, Nevada, United States
- MetroHealth Cancer Care Center at MetroHealth Medical Center — Cleveland, Ohio, United States
- Oklahoma University Cancer Institute — Oklahoma City, Oklahoma, United States
- Cancer Care Associates - Saint Francis Campus — Tulsa, Oklahoma, United States
- Parkland Memorial Hospital — Dallas, Texas, United States
- Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas — Dallas, Texas, United States
- Lyndon B. Johnson General Hospital — Houston, Texas, United States
- M. D. Anderson Cancer Center at University of Texas — Houston, Texas, United States
- Carilion Gynecologic Oncology Associates — Roanoke, Virginia, United States
Full record on ClinicalTrials.gov
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